| Date | Location | Result | |
| 03/05/06 | Hickory, NC (Catawba Valley CC) | Newberry College 57, Tusculum College 50 | Box score |
| 03/04/06 | CVCC Arena, Hickory, N.C. | Tusculum College 76, Carson-Newman College 59 | Box score |
| 03/01/06 | Greeneville, Tenn. (Pioneer Arena) | Tusculum 65, Catawba 59 | Box score |
| 02/25/06 | Hickory, N.C. (Shuford Gymnasium) | Tusculum 79, Lenoir-Rhyne 71 | Box score |
| 02/22/06 | Clinton, S.C. (Ross E. Templeton Center) | Presbyterian College 63, Tusculum College 62 | Box score |
| 02/18/06 | Greeneville, Tenn. (Pioneer Arena) | Tusculum 84, Newberry 71 | Box score |
| 02/15/06 | Greeneville, Tenn. (Pioneer Arena) | Carson-Newman 60, Tusculum 53 | Box score |
| 2-11-06 | Salisbury,NC (Goodman Gym) | Tusculum 73, Catawba Lady Indians 70 | Box score |
| 02/08/06 | Greeneville, Tenn. (Pioneer Arena) | Tusculum 92, Mars Hill 70 | Box score |
| 02/04/06 | Cuddy Arena, Wingate, N.C. | Wingate 68, Tusculum 62 | Box score |
| 01/28/06 | Greeneville, Tenn. (Pioneer Arena) | Tusculum 73, Lenoir-Rhyne 51 | Box score |
| 01/25/06 | Greeneville, Tenn. (Pioneer Arena) | Presbyterian 69, Tusculum 65 | Box score |
| 01/21/06 | Eleazer Arena, Newberry, S.C. | Newberry College 71, Tusculum College 67 | Box score |
| 1/18/06 | Jefferson City, Tenn./Holt Fieldhouse | Carson-Newman 69, Tusculum 67 | Box score |
| 1/14/06 | Greeneville, Tenn. (Pioneer Arena) | Tusculum 73, Catawba 58 | Box score |
| 01/11/06 | Mars Hill, NC (Stanford Arena) | Tusculum 83, Mars Hill College 68 | Box score |
| 01/07/06 | Greeneville, Tenn. (Pioneer Arena) | Wingate 82, Tusculum 72 | Box score |
| 12-17-05 | Savannah, Ga. (Alumni Arena) | Tusculum 66, Fayetteville State 62 | Box score |
| 12/16/05 | Savannah, Ga. (Alumni Arena) | Armstrong Atlantic 86, Tusculum 84 | Box score |
| 12/13/05 | Greeneville, Tenn. (Pioneer Arena) | Tusculum 75, Lincoln Memorial 46 | Box score |
| 12/10/05 | Greeneville, Tenn. (Pioneer Arena) | Tusculum 78, North Greenville 55 | Box score |
| 12/05/05 | Greeneville, Tenn. (Pioneer Arena) | Tusculum 80, Queens (N.C.) 56 | Box score |
| 12/03/05 | Harrogate, TN | Tusculum 71, Lincoln Memorial 59 | Box score |
| 11/26/05 | UNC Pembroke 60, Tusculum 48 | Box score | |
| 11/22/05 | Greeneville, Tenn. | Tusculum 74, Concord 60 | Box score |
| 11/19/05 | Greeneville, Tenn. | Tusculum 77, S.C. Upstate 69 | Box score |
| 11/18/05 | Greeneville, Tenn. | Tusculum 61, Johnson Smith 49 | Box score |
| 11/15/05 | Tigerville, S.C. | Tusculum 77, North Greenville 72 | Box score |